- The Black Keys (4,185,003 followers) blues rock, garage rock, modern blues, rock
- Stevie Ray Vaughan (2,658,818 followers) blues, blues rock, classic blues, southern rock, modern blues
- Joe Bonamassa (1,016,516 followers) blues, blues rock, modern blues, classic blues
- Gary Clark Jr. (986,961 followers) modern blues, blues rock, blues, soul blues
- Buddy Guy (894,225 followers) blues, classic blues, blues rock, modern blues, soul blues, country blues
- Johnny Winter (524,111 followers) blues, blues rock, classic blues, modern blues, southern rock
- Rory Gallagher (507,899 followers) blues rock, blues, modern blues, classic blues
- Tedeschi Trucks Band (504,322 followers) jam band, modern blues, blues rock, blues, southern rock
- Albert King (494,309 followers) blues, classic blues, blues rock, soul blues, modern blues
- Beth Hart (490,504 followers) blues, modern blues, blues rock
- Rival Sons (485,622 followers) blues rock, modern blues
- John Mayall & The Bluesbreakers (441,947 followers) blues, blues rock, classic blues, modern blues
- The Dead Weather (441,418 followers) garage rock, southern gothic, blues rock, modern blues
- Freddie King (426,495 followers) blues, classic blues, blues rock, modern blues
- Marcus King (391,926 followers) modern blues, blues rock
- Keb' Mo' (377,187 followers) blues, modern blues, country blues, blues rock, classic blues
- Kenny Wayne Shepherd (374,245 followers) blues rock, blues, modern blues, southern rock
- Gov't Mule (312,422 followers) jam band, southern rock, blues rock, modern blues, blues
- Larkin Poe (287,953 followers) blues rock, modern blues, blues, roots rock
- Robert Cray (273,715 followers) blues, modern blues, blues rock, soul blues, classic blues
- John Mayall (271,865 followers) blues, blues rock, modern blues, classic blues
- Robin Trower (271,159 followers) blues rock, blues, modern blues
- Jonny Lang (268,009 followers) blues, blues rock, modern blues
- The Marcus King Band (264,426 followers) modern blues, southern rock, blues rock, blues, jam band
- Taj Mahal (248,659 followers) blues, classic blues, country blues, blues rock, modern blues
- Christone "Kingfish" Ingram (244,168 followers) blues, modern blues, blues rock
- Black Pistol Fire (240,395 followers) blues rock, modern blues, garage rock
- The Derek Trucks Band (238,103 followers) jam band, modern blues, blues rock, southern rock, blues
- The Jeff Healey Band (237,699 followers) blues rock, blues, modern blues
- Susan Tedeschi (235,407 followers) modern blues, blues, blues rock
- Seasick Steve (225,628 followers) blues, modern blues, blues rock, country blues
- Albert Collins (219,261 followers) blues, classic blues, blues rock, modern blues
- JJ Grey & Mofro (209,109 followers) modern blues, jam band, southern rock, blues, blues rock
- Fantastic Negrito (208,258 followers) southern gothic, modern blues, blues rock, blues
- The Vaughan Brothers (195,597 followers) blues, blues rock, modern blues
- The Fabulous Thunderbirds (193,147 followers) blues, classic blues, blues rock, southern rock, modern blues
- Roy Buchanan (188,453 followers) blues, blues rock, classic blues, modern blues
- R.L. Burnside (178,021 followers) blues, country blues, modern blues, blues rock, classic blues
- Radio Moscow (172,165 followers) stoner rock, blues rock, modern blues, psychedelic rock, stoner metal, space rock, neo-psychedelic
- Richie Kotzen (169,131 followers) blues rock, funk rock, modern blues
- Cam Cole (155,727 followers) blues rock, modern blues
- Jimmie Vaughan (154,337 followers) blues, blues rock, classic blues, modern blues, soul blues
- Samantha Fish (153,732 followers) modern blues, blues, blues rock
- Warren Haynes (153,627 followers) southern rock, jam band, blues rock, modern blues, blues
- Anderson East (153,522 followers) modern blues
- Ghost Hounds (147,838 followers) blues rock, modern blues, southern rock, country rock, southern gothic
- Savoy Brown (146,507 followers) blues rock, blues, modern blues, psychedelic rock
- Alvin Lee (144,024 followers) blues, blues rock, modern blues
- The Record Company (134,126 followers) blues rock, modern blues, blues, roots rock
- Walter Trout (134,010 followers) blues, blues rock, modern blues, classic blues
- Vintage Trouble (132,022 followers) blues rock, modern blues, retro soul, blues, retro pop
- Junior Wells (128,815 followers) blues, classic blues, blues rock, modern blues, soul blues
- Black Country Communion (127,647 followers) blues rock, modern blues, hard rock
- The Paul Butterfield Blues Band (118,575 followers) blues, blues rock, classic blues, modern blues
- Robben Ford (118,425 followers) modern blues, blues, blues rock, soul blues, jazz fusion
- The Robert Cray Band (118,389 followers) blues, modern blues, blues rock, soul blues, classic blues
- Joanne Shaw Taylor (117,922 followers) blues, blues rock, modern blues
- Eric Gales (117,035 followers) modern blues, blues rock, blues
- North Mississippi Allstars (116,311 followers) southern rock, modern blues, jam band, blues rock, blues
- Benjamin Booker (106,733 followers) modern blues, blues rock
- The Bones of J.R. Jones (106,077 followers) southern gothic, blues rock, modern blues, country blues
- Tab Benoit (104,121 followers) blues, cajun, modern blues, zydeco, blues rock, country blues
- Robert Finley (103,777 followers) blues, soul blues, modern blues, southern gothic
- Black Joe Lewis & The Honeybears (102,758 followers) modern blues, blues rock, retro soul, roots rock, funk, blues
- Jeff Healey (101,793 followers) blues, blues rock, modern blues
- Tyler Bryant & the Shakedown (99,193 followers) blues rock, modern blues, southern rock, blues
- Pat Travers (98,177 followers) blues rock, southern rock, modern blues, blues
- Jackie Venson (93,878 followers) blues, modern blues, blues rock, soul blues
- Luther Allison (88,585 followers) blues, classic blues, modern blues, blues rock
- Philip Sayce (84,792 followers) blues rock, modern blues, blues
- Ana Popovic (84,278 followers) blues, modern blues, blues rock, soul blues, funk rock
- Popa Chubby (83,933 followers) blues rock, blues, modern blues
- Robert Randolph & The Family Band (82,021 followers) modern blues, jam band, blues, blues rock
- The Temperance Movement (77,425 followers) blues rock, modern blues
- James Cotton (75,927 followers) blues, classic blues, modern blues, blues rock
- Clarence "Gatemouth" Brown (74,436 followers) blues, classic blues, modern blues, zydeco, blues rock
- Eric Bibb (73,953 followers) blues, modern blues, country blues, classic blues
- Otis Taylor (70,320 followers) blues, country blues, blues rock, modern blues
- Chris Robinson Brotherhood (70,046 followers) jam band, southern rock, modern blues
- The Stone Foxes (68,789 followers) blues rock, modern blues
- Anders Osborne (66,873 followers) modern blues, jam band, blues rock
- Billy F Gibbons (65,699 followers) blues rock, blues, modern blues
- Left Lane Cruiser (64,813 followers) blues rock, modern blues, stoner rock, blues, country blues, garage rock
- Scott Henderson (64,457 followers) jazz fusion, jazz funk, modern blues
- Jack Broadbent (61,376 followers) modern blues, blues rock, blues, southern gothic, country blues
- Sonny Landreth (61,199 followers) blues, blues rock, modern blues, cajun, zydeco
- Charlie Musselwhite (60,215 followers) blues, modern blues, classic blues, blues rock
- The Parlor Mob (60,090 followers) blues rock, modern blues
- Shemekia Copeland (56,779 followers) blues, modern blues, blues rock, soul blues, classic blues
- Aynsley Lister (55,547 followers) blues, blues rock, modern blues
- Tinsley Ellis (55,401 followers) blues, blues rock, modern blues
- Quaker City Night Hawks (54,160 followers) blues rock, modern blues, southern rock, southern gothic
- Albert Cummings (53,976 followers) blues, blues rock, modern blues
- Coco Montoya (53,751 followers) blues, blues rock, modern blues
- Beth Hart, Joe Bonamassa (53,193 followers) blues, blues rock, modern blues, soul blues
- Doyle Bramhall II (53,113 followers) modern blues, blues rock, blues
- The Cold Stares (52,277 followers) blues rock, modern blues, blues
- Ash Grunwald (52,179 followers) blues, modern blues, blues rock
- Tommy Castro (52,150 followers) blues, blues rock, modern blues, soul blues
- Matt Andersen (51,732 followers) blues, modern blues