- The Black Keys (4,258,422 followers) blues rock, garage rock, modern blues, rock
- Stevie Ray Vaughan (2,708,021 followers) blues rock, classic blues, blues, southern rock, modern blues, classic rock
- Joe Bonamassa (1,040,508 followers) blues rock, modern blues, blues, classic blues
- Gary Clark Jr. (1,001,998 followers) modern blues, blues rock, soul blues
- Buddy Guy (913,623 followers) classic blues, blues, blues rock, modern blues, soul blues, country blues
- Gary Moore (908,372 followers) blues rock, blues, modern blues
- Johnny Winter (529,443 followers) blues rock, classic blues, blues, modern blues, southern rock
- Tedeschi Trucks Band (529,383 followers) jam band, modern blues, blues rock, southern rock, blues
- Rory Gallagher (524,272 followers) blues rock, modern blues, classic blues, blues
- Beth Hart (506,918 followers) blues, blues rock, modern blues
- Albert King (506,480 followers) classic blues, blues, blues rock, soul blues, modern blues
- Rival Sons (494,823 followers) blues rock, modern blues
- The Dead Weather (448,382 followers) garage rock, southern gothic, blues rock, modern blues
- John Mayall & The Bluesbreakers (446,968 followers) blues rock, classic blues, blues, modern blues
- Freddie King (435,000 followers) classic blues, blues, blues rock, soul blues, modern blues
- Marcus King (417,352 followers) modern blues, blues rock
- Keb' Mo' (385,374 followers) modern blues, blues, country blues, blues rock, classic blues, soul blues
- Kenny Wayne Shepherd (384,768 followers) blues rock, modern blues, blues, southern rock
- Gov't Mule (318,620 followers) jam band, southern rock, blues rock, modern blues, blues
- Larkin Poe (295,960 followers) blues rock, modern blues, blues, roots rock
- Robert Cray (278,613 followers) modern blues, blues rock, blues, soul blues, classic blues
- Robin Trower (278,591 followers) blues rock, modern blues
- The Marcus King Band (278,427 followers) modern blues, southern rock, blues rock, jam band, country blues
- John Mayall (275,508 followers) blues rock, blues, modern blues, classic blues, soul blues
- Jonny Lang (273,462 followers) blues rock, modern blues, blues, classic blues
- Taj Mahal (257,822 followers) classic blues, blues, country blues, blues rock, modern blues
- Christone "Kingfish" Ingram (253,262 followers) modern blues, blues rock, blues, classic blues, soul blues
- Black Pistol Fire (245,967 followers) blues rock, modern blues, garage rock
- The Jeff Healey Band (243,186 followers) blues rock, blues, modern blues
- The Derek Trucks Band (241,976 followers) jam band, modern blues, blues rock, southern rock, blues
- Susan Tedeschi (241,627 followers) blues, modern blues, blues rock
- Seasick Steve (229,819 followers) modern blues, blues rock, country blues
- Albert Collins (225,468 followers) classic blues, blues, blues rock, modern blues, soul blues
- JJ Grey & Mofro (216,693 followers) modern blues, jam band, southern rock, blues rock
- Fantastic Negrito (214,720 followers) southern gothic, modern blues, blues rock
- The Vaughan Brothers (198,329 followers) blues rock, blues, modern blues, southern rock, classic blues
- The Fabulous Thunderbirds (196,662 followers) classic blues, blues rock, southern rock, blues, modern blues
- Roy Buchanan (194,083 followers) blues, blues rock, classic blues, modern blues
- Otis Rush (190,554 followers) classic blues, blues, blues rock, soul blues, modern blues
- R.L. Burnside (190,505 followers) country blues, modern blues, blues rock, classic blues, blues
- Radio Moscow (174,585 followers) stoner rock, blues rock, modern blues, psychedelic rock, stoner metal, space rock, neo-psychedelic, acid rock, garage rock
- Richie Kotzen (172,145 followers) blues rock, funk rock, modern blues
- Cam Cole (166,946 followers) blues rock, modern blues
- Samantha Fish (160,426 followers) blues, modern blues, blues rock, country blues
- Jimmie Vaughan (157,665 followers) blues rock, blues, classic blues, modern blues, soul blues
- Warren Haynes (156,713 followers) southern rock, jam band, blues rock, modern blues
- Anderson East (156,172 followers) modern blues
- Ghost Hounds (150,124 followers) blues rock, southern rock, modern blues, country rock, southern gothic, country blues
- Savoy Brown (148,665 followers) blues rock, modern blues, psychedelic rock, blues
- Snowy White (147,483 followers) blues, blues rock, modern blues
- Alvin Lee (146,368 followers) blues rock, blues, modern blues
- Koko Taylor (141,090 followers) classic blues, blues, soul blues, blues rock, modern blues
- The Record Company (139,390 followers) blues rock, modern blues, roots rock
- Walter Trout (136,575 followers) blues rock, modern blues, blues, classic blues
- Vintage Trouble (133,632 followers) blues rock, modern blues, retro soul, soul blues, retro pop
- Junior Wells (131,102 followers) classic blues, blues, blues rock, modern blues, soul blues
- Black Country Communion (129,948 followers) blues rock, modern blues, hard rock
- Eric Gales (122,935 followers) modern blues, blues rock, blues, classic blues
- Robben Ford (122,110 followers) modern blues, blues rock, blues, jazz fusion, soul blues, classic blues
- Joanne Shaw Taylor (121,356 followers) blues, blues rock, modern blues, classic blues, soul blues
- The Paul Butterfield Blues Band (121,321 followers) blues rock, classic blues, blues, modern blues
- The Robert Cray Band (120,413 followers) modern blues, blues rock, blues, soul blues, classic blues
- North Mississippi Allstars (118,742 followers) southern rock, modern blues, jam band, blues rock, roots rock
- The Bones of J.R. Jones (112,120 followers) southern gothic, blues rock, modern blues, country blues
- Tab Benoit (108,721 followers) cajun, modern blues, zydeco, blues rock, blues, country blues
- Benjamin Booker (107,959 followers) modern blues, blues rock
- Robert Finley (107,300 followers) soul blues, modern blues, southern gothic, blues rock
- Black Joe Lewis & The Honeybears (105,152 followers) modern blues, blues rock, retro soul, roots rock, funk
- Jackie Venson (104,702 followers) blues, modern blues, blues rock, soul blues
- Jeff Healey (104,352 followers) blues rock, modern blues, blues, classic blues
- Mike Bloomfield (100,886 followers) classic blues, blues, blues rock, modern blues
- Tyler Bryant & the Shakedown (100,691 followers) blues rock, modern blues, southern rock
- Pat Travers (100,081 followers) blues rock, southern rock, modern blues
- Luther Allison (90,749 followers) classic blues, blues, blues rock, modern blues, soul blues
- Philip Sayce (89,372 followers) blues rock, modern blues, blues
- Ana Popovic (86,401 followers) blues, modern blues, blues rock, soul blues, funk rock
- Junior Kimbrough (85,846 followers) country blues, classic blues, blues, modern blues, blues rock
- Popa Chubby (85,342 followers) blues rock, modern blues, blues
- Gugun Blues Shelter (85,169 followers) indonesian rock, indonesian indie, indorock, blues rock, indonesian r&b, modern blues
- Robert Randolph & The Family Band (84,197 followers) modern blues, jam band, blues rock
- The Temperance Movement (80,740 followers) blues rock, modern blues, southern rock
- Clarence "Gatemouth" Brown (79,463 followers) classic blues, blues, modern blues, zydeco, blues rock, cajun, boogie-woogie
- James Cotton (77,278 followers) classic blues, blues, modern blues, blues rock, soul blues
- Eric Bibb (77,250 followers) modern blues, country blues, blues, classic blues, blues rock
- Otis Taylor (72,880 followers) country blues, blues rock, modern blues
- Mississippi Fred McDowell (71,965 followers) classic blues, country blues, blues, modern blues
- Chris Robinson Brotherhood (70,864 followers) jam band, southern rock, modern blues, blues rock
- Jimmy Rogers (70,056 followers) classic blues, blues, soul blues, blues rock, modern blues
- The Stone Foxes (69,904 followers) blues rock, modern blues, roots rock
- Billy F Gibbons (69,098 followers) blues rock, modern blues
- Anders Osborne (69,009 followers) modern blues, jam band, blues rock
- Left Lane Cruiser (66,625 followers) blues rock, modern blues, stoner rock, garage rock, country blues
- Scott Henderson (66,397 followers) jazz fusion, jazz funk, modern blues
- Charlie Musselwhite (62,717 followers) modern blues, blues, classic blues, blues rock
- Sonny Landreth (62,578 followers) blues rock, modern blues, blues, cajun, zydeco
- Jack Broadbent (62,268 followers) modern blues, blues rock, southern gothic, country blues
- The Parlor Mob (61,676 followers) blues rock, modern blues
- Hound Dog Taylor (60,200 followers) classic blues, blues, blues rock, modern blues
- Shemekia Copeland (58,571 followers) blues, modern blues, blues rock, soul blues, classic blues
- Beth Hart, Joe Bonamassa (58,539 followers) blues rock, blues, modern blues, soul blues