- Jimi Hendrix (7,740,227 followers) psychedelic rock, classic rock, acid rock, blues rock
- Eric Clapton (6,929,652 followers) blues rock, classic rock
- ZZ Top (5,238,756 followers) southern rock, classic rock, blues rock, rock
- The Black Keys (4,258,422 followers) blues rock, garage rock, modern blues, rock
- The White Stripes (3,788,956 followers) garage rock, blues rock, rock, alternative rock
- B.B. King (2,938,203 followers) classic blues, blues, blues rock, soul blues
- Cream (2,799,534 followers) classic rock, psychedelic rock, acid rock, blues rock
- Stevie Ray Vaughan (2,708,021 followers) blues rock, classic blues, blues, southern rock, modern blues, classic rock
- Allman Brothers Band (1,919,709 followers) southern rock, jam band, classic rock, blues rock, country rock
- Jack White (1,490,554 followers) blues rock, garage rock
- Muddy Waters (1,392,428 followers) classic blues, blues, blues rock, soul blues, country blues
- George Thorogood & The Destroyers (1,093,848 followers) classic rock, blues rock, southern rock
- Joe Bonamassa (1,040,508 followers) blues rock, modern blues, blues, classic blues
- The Yardbirds (1,007,928 followers) psychedelic rock, acid rock, blues rock
- Gary Clark Jr. (1,001,998 followers) modern blues, blues rock, soul blues
- John Lee Hooker (952,839 followers) classic blues, blues, blues rock, country blues, soul blues
- Buddy Guy (913,623 followers) classic blues, blues, blues rock, modern blues, soul blues, country blues
- Gary Moore (908,372 followers) blues rock, blues, modern blues
- Derek & The Dominos (904,736 followers) blues rock, classic rock
- J.J. Cale (880,568 followers) roots rock, blues rock
- Status Quo (874,242 followers) glam rock, blues rock
- Jeff Beck (871,501 followers) jazz fusion, blues rock
- Canned Heat (703,245 followers) blues rock
- Ten Years After (658,883 followers) blues rock, psychedelic rock
- Robert Johnson (651,433 followers) classic blues, country blues, blues, blues rock
- Free (634,317 followers) classic rock, blues rock
- Black Rebel Motorcycle Club (604,218 followers) southern gothic, garage rock, blues rock
- Jimmy Page (585,651 followers) blues rock
- Howlin' Wolf (582,228 followers) classic blues, blues, blues rock, country blues, soul blues
- Johnny Winter (529,443 followers) blues rock, classic blues, blues, modern blues, southern rock
- Tedeschi Trucks Band (529,383 followers) jam band, modern blues, blues rock, southern rock, blues
- Rory Gallagher (524,272 followers) blues rock, modern blues, classic blues, blues
- Beth Hart (506,918 followers) blues, blues rock, modern blues
- Albert King (506,480 followers) classic blues, blues, blues rock, soul blues, modern blues
- Rival Sons (494,823 followers) blues rock, modern blues
- The Blues Brothers (470,265 followers) blues, blues rock
- The Dead Weather (448,382 followers) garage rock, southern gothic, blues rock, modern blues
- John Mayall & The Bluesbreakers (446,968 followers) blues rock, classic blues, blues, modern blues
- Freddie King (435,000 followers) classic blues, blues, blues rock, soul blues, modern blues
- Marcus King (417,352 followers) modern blues, blues rock
- All Them Witches (389,004 followers) stoner rock, stoner metal, neo-psychedelic, psychedelic rock, space rock, sludge metal, blues rock
- Keb' Mo' (385,374 followers) modern blues, blues, country blues, blues rock, classic blues, soul blues
- Kenny Wayne Shepherd (384,768 followers) blues rock, modern blues, blues, southern rock
- Dan Auerbach (384,422 followers) blues rock
- Humble Pie (376,331 followers) blues rock, classic rock
- Mountain (371,240 followers) classic rock, blues rock, southern rock
- Gregg Allman (333,201 followers) southern rock, country rock, jam band, blues rock
- Gov't Mule (318,620 followers) jam band, southern rock, blues rock, modern blues, blues
- Lightnin' Hopkins (296,433 followers) classic blues, country blues, blues, blues rock, soul blues
- Larkin Poe (295,960 followers) blues rock, modern blues, blues, roots rock
- Robert Cray (278,613 followers) modern blues, blues rock, blues, soul blues, classic blues
- Robin Trower (278,591 followers) blues rock, modern blues
- The Marcus King Band (278,427 followers) modern blues, southern rock, blues rock, jam band, country blues
- John Mayall (275,508 followers) blues rock, blues, modern blues, classic blues, soul blues
- Jonny Lang (273,462 followers) blues rock, modern blues, blues, classic blues
- Peter Green (265,291 followers) blues rock, blues, classic blues
- The Blue Stones (258,844 followers) blues rock
- Taj Mahal (257,822 followers) classic blues, blues, country blues, blues rock, modern blues
- Christone "Kingfish" Ingram (253,262 followers) modern blues, blues rock, blues, classic blues, soul blues
- Black Pistol Fire (245,967 followers) blues rock, modern blues, garage rock
- The Jeff Healey Band (243,186 followers) blues rock, blues, modern blues
- The Derek Trucks Band (241,976 followers) jam band, modern blues, blues rock, southern rock, blues
- Susan Tedeschi (241,627 followers) blues, modern blues, blues rock
- Little Walter (235,455 followers) classic blues, blues, soul blues, blues rock
- Seasick Steve (229,819 followers) modern blues, blues rock, country blues
- T-Bone Walker (229,472 followers) classic blues, blues, blues rock, soul blues
- Albert Collins (225,468 followers) classic blues, blues, blues rock, modern blues, soul blues
- Graveyard (220,944 followers) stoner rock, stoner metal, sludge metal, blues rock, space rock, doom metal
- Reignwolf (217,397 followers) blues rock
- JJ Grey & Mofro (216,693 followers) modern blues, jam band, southern rock, blues rock
- Fantastic Negrito (214,720 followers) southern gothic, modern blues, blues rock
- Elmore James (213,436 followers) classic blues, blues, blues rock, soul blues
- Sonny Boy Williamson II (208,414 followers) classic blues, blues, country blues, blues rock, soul blues
- The Vaughan Brothers (198,329 followers) blues rock, blues, modern blues, southern rock, classic blues
- The Fabulous Thunderbirds (196,662 followers) classic blues, blues rock, southern rock, blues, modern blues
- Roy Buchanan (194,083 followers) blues, blues rock, classic blues, modern blues
- Otis Rush (190,554 followers) classic blues, blues, blues rock, soul blues, modern blues
- R.L. Burnside (190,505 followers) country blues, modern blues, blues rock, classic blues, blues
- Radio Moscow (174,585 followers) stoner rock, blues rock, modern blues, psychedelic rock, stoner metal, space rock, neo-psychedelic, acid rock, garage rock
- Richie Kotzen (172,145 followers) blues rock, funk rock, modern blues
- Blues Saraceno (172,093 followers) southern gothic, blues rock, country rock, country blues
- Tony Joe White (171,168 followers) blues rock, blues, country blues, cajun
- Son House (170,545 followers) classic blues, country blues, blues, blues rock
- Duane Allman (169,649 followers) southern rock, blues rock, classic blues
- Willie Dixon (169,440 followers) classic blues, blues, blues rock, soul blues
- Cam Cole (166,946 followers) blues rock, modern blues
- George Thorogood (165,525 followers) blues rock
- Samantha Fish (160,426 followers) blues, modern blues, blues rock, country blues
- Jimmie Vaughan (157,665 followers) blues rock, blues, classic blues, modern blues, soul blues
- Warren Haynes (156,713 followers) southern rock, jam band, blues rock, modern blues
- Jimmy Reed (151,412 followers) classic blues, blues, blues rock, soul blues
- Ghost Hounds (150,124 followers) blues rock, southern rock, modern blues, country rock, southern gothic, country blues
- Savoy Brown (148,665 followers) blues rock, modern blues, psychedelic rock, blues
- The Sheepdogs (147,659 followers) southern rock, blues rock
- Snowy White (147,483 followers) blues, blues rock, modern blues
- Alvin Lee (146,368 followers) blues rock, blues, modern blues
- Goodbye June (144,845 followers) blues rock
- Koko Taylor (141,090 followers) classic blues, blues, soul blues, blues rock, modern blues
- The Record Company (139,390 followers) blues rock, modern blues, roots rock
- Walter Trout (136,575 followers) blues rock, modern blues, blues, classic blues