- Jimi Hendrix (7,539,754 followers) psychedelic rock, classic rock, acid rock, blues rock
- Eric Clapton (6,753,283 followers) blues, blues rock, classic rock
- ZZ Top (5,069,361 followers) southern rock, classic rock, blues rock, rock
- The Black Keys (4,185,003 followers) blues rock, garage rock, modern blues, rock
- The White Stripes (3,655,442 followers) garage rock, blues rock, rock, alternative rock
- B.B. King (2,891,271 followers) blues, classic blues, soul blues, blues rock
- Cream (2,715,032 followers) classic rock, psychedelic rock, acid rock, blues rock
- Stevie Ray Vaughan (2,658,818 followers) blues, blues rock, classic blues, southern rock, modern blues
- Allman Brothers Band (1,860,280 followers) southern rock, jam band, classic rock, blues rock, country rock
- Jack White (1,439,761 followers) blues rock, garage rock
- Muddy Waters (1,369,652 followers) blues, classic blues, blues rock, soul blues, country blues
- George Thorogood & The Destroyers (1,054,605 followers) classic rock, blues rock, southern rock
- Joe Bonamassa (1,016,516 followers) blues, blues rock, modern blues, classic blues
- The Yardbirds (996,554 followers) psychedelic rock, acid rock, blues rock
- Gary Clark Jr. (986,961 followers) modern blues, blues rock, blues, soul blues
- John Lee Hooker (933,999 followers) blues, classic blues, blues rock, country blues, soul blues
- Buddy Guy (894,225 followers) blues, classic blues, blues rock, modern blues, soul blues, country blues
- Gary Moore (863,884 followers) blues, blues rock
- J.J. Cale (860,822 followers) blues, blues rock, roots rock
- Derek & The Dominos (860,433 followers) blues rock, classic rock
- Status Quo (856,472 followers) glam rock, blues rock
- Jeff Beck (850,808 followers) jazz fusion, blues rock, blues
- Canned Heat (684,560 followers) blues rock, blues
- Ten Years After (642,149 followers) blues rock, psychedelic rock
- Free (609,047 followers) classic rock, blues rock
- Black Rebel Motorcycle Club (594,117 followers) southern gothic, garage rock, blues rock
- Jimmy Page (580,351 followers) blues rock, blues
- Howlin' Wolf (568,025 followers) blues, classic blues, blues rock
- Johnny Winter (524,111 followers) blues, blues rock, classic blues, modern blues, southern rock
- Rory Gallagher (507,899 followers) blues rock, blues, modern blues, classic blues
- Tedeschi Trucks Band (504,322 followers) jam band, modern blues, blues rock, blues, southern rock
- Albert King (494,309 followers) blues, classic blues, blues rock, soul blues, modern blues
- Beth Hart (490,504 followers) blues, modern blues, blues rock
- Rival Sons (485,622 followers) blues rock, modern blues
- The Blues Brothers (455,214 followers) blues, blues rock
- John Mayall & The Bluesbreakers (441,947 followers) blues, blues rock, classic blues, modern blues
- The Dead Weather (441,418 followers) garage rock, southern gothic, blues rock, modern blues
- Freddie King (426,495 followers) blues, classic blues, blues rock, modern blues
- Marcus King (391,926 followers) modern blues, blues rock
- Dan Auerbach (377,976 followers) blues rock
- Keb' Mo' (377,187 followers) blues, modern blues, country blues, blues rock, classic blues
- Kenny Wayne Shepherd (374,245 followers) blues rock, blues, modern blues, southern rock
- Humble Pie (370,061 followers) blues rock
- All Them Witches (366,444 followers) stoner rock, stoner metal, neo-psychedelic, psychedelic rock, space rock, sludge metal, blues rock
- Mountain (355,214 followers) classic rock, blues rock, southern rock
- Gregg Allman (321,819 followers) southern rock, country rock, jam band, blues rock, blues
- Gov't Mule (312,422 followers) jam band, southern rock, blues rock, modern blues, blues
- Larkin Poe (287,953 followers) blues rock, modern blues, blues, roots rock
- Robert Cray (273,715 followers) blues, modern blues, blues rock, soul blues, classic blues
- John Mayall (271,865 followers) blues, blues rock, modern blues, classic blues
- Robin Trower (271,159 followers) blues rock, blues, modern blues
- Jonny Lang (268,009 followers) blues, blues rock, modern blues
- The Marcus King Band (264,426 followers) modern blues, southern rock, blues rock, blues, jam band
- Peter Green (260,445 followers) blues, blues rock, classic blues
- Taj Mahal (248,659 followers) blues, classic blues, country blues, blues rock, modern blues
- The Blue Stones (247,206 followers) blues rock
- Christone "Kingfish" Ingram (244,168 followers) blues, modern blues, blues rock
- Black Pistol Fire (240,395 followers) blues rock, modern blues, garage rock
- The Derek Trucks Band (238,103 followers) jam band, modern blues, blues rock, southern rock, blues
- The Jeff Healey Band (237,699 followers) blues rock, blues, modern blues
- Susan Tedeschi (235,407 followers) modern blues, blues, blues rock
- Seasick Steve (225,628 followers) blues, modern blues, blues rock, country blues
- Albert Collins (219,261 followers) blues, classic blues, blues rock, modern blues
- Graveyard (217,550 followers) stoner rock, stoner metal, sludge metal, blues rock, space rock, doom metal
- Reignwolf (213,736 followers) blues rock
- JJ Grey & Mofro (209,109 followers) modern blues, jam band, southern rock, blues, blues rock
- Elmore James (208,758 followers) blues, classic blues, blues rock
- Fantastic Negrito (208,258 followers) southern gothic, modern blues, blues rock, blues
- Sonny Boy Williamson II (203,137 followers) blues, classic blues, country blues, blues rock
- The Vaughan Brothers (195,597 followers) blues, blues rock, modern blues
- The Fabulous Thunderbirds (193,147 followers) blues, classic blues, blues rock, southern rock, modern blues
- Roy Buchanan (188,453 followers) blues, blues rock, classic blues, modern blues
- Otis Rush (187,081 followers) classic blues, blues, blues rock, soul blues
- R.L. Burnside (178,021 followers) blues, country blues, modern blues, blues rock, classic blues
- Radio Moscow (172,165 followers) stoner rock, blues rock, modern blues, psychedelic rock, stoner metal, space rock, neo-psychedelic
- Richie Kotzen (169,131 followers) blues rock, funk rock, modern blues
- Blues Saraceno (167,815 followers) southern gothic, blues rock, country rock, country blues
- Duane Allman (166,892 followers) southern rock, blues, blues rock
- George Thorogood (164,857 followers) blues rock, blues
- Tony Joe White (162,635 followers) blues, blues rock
- Cam Cole (155,727 followers) blues rock, modern blues
- Jimmie Vaughan (154,337 followers) blues, blues rock, classic blues, modern blues, soul blues
- Samantha Fish (153,732 followers) modern blues, blues, blues rock
- Warren Haynes (153,627 followers) southern rock, jam band, blues rock, modern blues, blues
- Ghost Hounds (147,838 followers) blues rock, modern blues, southern rock, country rock, southern gothic
- Savoy Brown (146,507 followers) blues rock, blues, modern blues, psychedelic rock
- Alvin Lee (144,024 followers) blues, blues rock, modern blues
- The Sheepdogs (141,070 followers) blues rock
- Goodbye June (140,666 followers) blues rock
- Snowy White (140,126 followers) blues, blues rock
- The Record Company (134,126 followers) blues rock, modern blues, blues, roots rock
- Walter Trout (134,010 followers) blues, blues rock, modern blues, classic blues
- Blues Pills (132,509 followers) stoner rock, blues rock, stoner metal
- Vintage Trouble (132,022 followers) blues rock, modern blues, retro soul, blues, retro pop
- Junior Wells (128,815 followers) blues, classic blues, blues rock, modern blues, soul blues
- Black Country Communion (127,647 followers) blues rock, modern blues, hard rock
- Justin Johnson (123,371 followers) blues, southern gothic, country blues, blues rock
- The Jon Spencer Blues Explosion (121,374 followers) garage rock, blues rock
- The Paul Butterfield Blues Band (118,575 followers) blues, blues rock, classic blues, modern blues
- Robben Ford (118,425 followers) modern blues, blues, blues rock, soul blues, jazz fusion