- LATIN MAFIA (2,038,096 followers) latin r&b
- Yoss Bones (649,671 followers) mexican hip hop, latin hip hop, latin r&b
- Nsqk (640,102 followers) latin r&b
- 3AM (607,188 followers) latin r&b
- Samantha Barrón (393,945 followers) latin r&b, mexican hip hop
- Leon Leiden (235,305 followers) latin r&b
- Chris Wandell (227,858 followers) latin r&b, trap latino
- Jesse Baez (215,336 followers) latin r&b, latin indie
- Girl Ultra (176,383 followers) latin indie, latin r&b, mexican indie, latin alternative
- Amarion (171,748 followers) trap latino, latin r&b
- Cardellino (159,604 followers) latin r&b
- legallyrxx (150,505 followers) latin r&b, reggaeton mexa
- Ramon Vega (147,912 followers) latin r&b
- AQUIHAYAQUIHAY (126,260 followers) latin r&b
- Panther (115,209 followers) argentine trap, latin r&b
- paopao (111,645 followers) urbano latino, latin r&b
- Saak (96,111 followers) latin r&b
- Vanessa Zamora (95,992 followers) latin indie, mexican indie, latin alternative, latin r&b
- A.C.O (90,951 followers) latin hip hop, latin r&b, reggae en español
- Lvtin Mvfia (90,761 followers) latin r&b
- Irepelusa (90,474 followers) latin r&b, latin indie
- Choclock (76,286 followers) latin r&b
- Lee Eye (74,943 followers) latin r&b
- Donovan Morales (72,948 followers) latin indie, latin r&b
- RMAND (69,766 followers) latin r&b
- Chita (68,465 followers) latin r&b
- E-Lhoy (68,177 followers) latin r&b
- Eva Ruiz (66,645 followers) latin r&b
- Ms. Ambar (65,583 followers) latin r&b, mexican hip hop
- Motherflowers (63,926 followers) latin r&b
- Dani Barranco (63,486 followers) latin r&b
- Méne (62,022 followers) latin r&b, latin indie
- G Sony (59,221 followers) latin r&b
- Pau Laggies (58,948 followers) latin r&b, latin indie, mexican indie
- Liana Malva (57,188 followers) latin r&b, latin hip hop
- Selene (55,449 followers) latin r&b, reggaeton mexa
- LUANA (54,480 followers) latin r&b
- Kiddie Gang (52,513 followers) latin r&b
- Aleesha (51,688 followers) latin r&b
- Absa G. (51,277 followers) latin r&b, mexican hip hop
- Kei Linch (49,314 followers) latin r&b, latin hip hop
- María Isabel (49,276 followers) latin r&b
- New Ridaz (47,478 followers) latin r&b
- Lui5 (46,161 followers) latin r&b
- Jovaan (45,969 followers) trap latino, latin r&b
- Mabiland (43,407 followers) latin r&b, latin alternative
- Shantty (43,397 followers) latin r&b
- Daymé Arocena (41,868 followers) latin jazz, afro-cuban jazz, latin r&b
- SOULFIA (41,690 followers) latin r&b, reggaeton chileno, chilean trap
- Jos Canela (41,662 followers) latin r&b
- Paula Cendejas (39,609 followers) latin r&b
- ELYSANIJ (38,332 followers) latin r&b
- ODDLIQUOR (37,808 followers) latin r&b
- Ka-b (37,262 followers) latin r&b
- eydrey (37,204 followers) latin r&b
- Laura Pérez (36,827 followers) latin indie, latin r&b
- LA GURU (36,770 followers) latin r&b
- Remers (36,355 followers) trap latino, latin r&b
- Marval (34,986 followers) latin r&b
- Nicole Horts (34,311 followers) latin r&b, latin indie
- BeatBoy (33,543 followers) reggaeton mexa, electro corridos, dembow belico, latin r&b
- Catana (33,436 followers) chilean trap, latin r&b
- day2k (32,901 followers) latin r&b
- Ninjiizu (32,412 followers) latin r&b
- Zizzy (31,816 followers) latin r&b, reggaeton mexa
- YOSHI (31,560 followers) latin r&b
- Nicole Favre (31,288 followers) latin r&b
- Met Music (30,936 followers) chilean trap, latin r&b, neoperreo
- Riosse (30,321 followers) latin r&b
- Yashua (29,986 followers) latin r&b
- P.FLXWS (28,549 followers) latin r&b
- An Espil (27,685 followers) latin r&b
- Sanchz (27,492 followers) jersey club, latin r&b
- Lara Project (27,389 followers) latin indie, latin r&b, latin alternative
- RoseAngel (27,332 followers) latin r&b
- NEZZA (27,120 followers) latin r&b
- DEVA (27,008 followers) latin r&b
- Lucauy (26,898 followers) latin r&b
- Shyno (26,334 followers) latin r&b
- ALONG (26,260 followers) latin r&b
- Yarge (26,230 followers) latin r&b
- Ferraz (26,173 followers) latin r&b, latin indie
- Fer Casillas (25,284 followers) latin r&b, mexican indie
- Yoandri (24,681 followers) latin r&b
- Leanys (24,521 followers) latin indie, latin r&b
- LATENIGHTJIGGY (23,950 followers) latin r&b
- Noa Sainz (23,132 followers) latin r&b, latin indie
- Desert Niños (22,373 followers) latin r&b, mexican hip hop
- La Gabi (21,927 followers) latin r&b, latin afrobeats
- Kimberley Tell (21,610 followers) latin r&b, latin indie
- FABRO (21,407 followers) latin r&b
- DIA (21,304 followers) latin r&b
- Dariel Amant (21,249 followers) latin r&b
- Seamoon (20,454 followers) latin r&b, latin hip hop
- Bella Dose (20,275 followers) latin r&b
- Miranda Santizo (20,145 followers) latin r&b, latin indie
- Astronautiko (20,068 followers) latin r&b, latin hip hop
- Sofish (19,780 followers) latin r&b
- Gama (19,700 followers) latin house, techengue, latin r&b
- Sebastian Urdiales (18,658 followers) latin r&b