- Bad Gyal (2,286,655 followers) neoperreo
- Tokischa (1,725,571 followers) dembow, neoperreo
- Yung Beef (707,416 followers) neoperreo
- Arca (669,944 followers) neoperreo, experimental, art pop, hyperpop
- Kaydy Cain (553,772 followers) neoperreo
- La Mafia del Amor (515,078 followers) neoperreo
- Cachirula (403,410 followers) reggaeton mexa, guaracha, neoperreo, reggaeton
- rusowsky (392,517 followers) neoperreo
- Villano Antillano (381,533 followers) neoperreo
- La Zowi (309,872 followers) neoperreo
- Princesa Alba (269,239 followers) chilean trap, neoperreo
- Soto Asa (242,588 followers) neoperreo
- Ms Nina (186,570 followers) neoperreo
- TAICHU (182,628 followers) neoperreo, argentine trap
- Sayuri & Sopholov (174,545 followers) reggaeton mexa, neoperreo
- Yeyo (159,956 followers) reggaeton mexa, neoperreo
- AKRIILA (154,738 followers) neoperreo, chilean trap
- Sailorfag (153,707 followers) neoperreo
- Alu Mix (147,970 followers) reggaeton mexa, neoperreo, reggaeton
- Gianluca (144,913 followers) chilean trap, neoperreo, reggaeton chileno
- Sara Hebe (137,354 followers) neoperreo, electrocumbia, latin hip hop
- Ceaese (135,662 followers) chilean trap, neoperreo, reggaeton chileno, chilean mambo
- Metrika (119,207 followers) neoperreo
- Albany (117,608 followers) neoperreo
- Six Sex (113,081 followers) neoperreo
- El High (111,685 followers) reggaeton chileno, reggaeton mexa, neoperreo
- Doony Graff (101,314 followers) reggaeton mexa, neoperreo
- EMJAY (95,668 followers) neoperreo
- SINAKA (93,036 followers) reggaeton chileno, neoperreo, chilean trap
- Isabella Lovestory (89,111 followers) neoperreo
- Loyaltty (87,689 followers) guaracha, reggaeton chileno, chilean trap, neoperreo, chilean mambo
- Juicy BAE (80,933 followers) neoperreo
- La Obsesion (79,455 followers) reggaeton mexa, neoperreo
- LOOJAN (78,556 followers) reggaeton mexa, neoperreo, reggaeton
- l0rna (75,040 followers) neoperreo
- La Goony (75,016 followers) neoperreo
- Tomasa del Real (73,178 followers) neoperreo
- RIXXIA (64,697 followers) reggaeton mexa, neoperreo
- 8belial (63,088 followers) neoperreo
- Luna Ki (59,302 followers) neoperreo
- BEA PELEA (53,023 followers) neoperreo
- Dinamarca (50,932 followers) neoperreo
- Afrojuice 195 (44,917 followers) neoperreo
- Kid Lucilfer (44,044 followers) chilean trap, neoperreo
- FaceBrooklyn (42,577 followers) reggaeton chileno, neoperreo, chilean trap
- KUINA (38,907 followers) neoperreo, chilean trap
- Ezya (38,342 followers) reggaeton mexa, neoperreo
- JEDET (37,744 followers) neoperreo
- Safety Trance (37,157 followers) neoperreo, experimental
- Chocolate Remix (36,894 followers) neoperreo
- Chzter (36,478 followers) neoperreo, reggaeton mexa
- Goa (35,165 followers) neoperreo
- La Favi (32,607 followers) neoperreo
- AMORE (31,548 followers) neoperreo
- Met Music (30,936 followers) chilean trap, latin r&b, neoperreo
- Sayuri (29,755 followers) reggaeton mexa, neoperreo
- nusar3000 (29,613 followers) neoperreo
- Alexis Mvgler (29,582 followers) neoperreo
- Xiyo (29,320 followers) neoperreo
- Meth Math (28,250 followers) neoperreo
- El Bugg (27,840 followers) neoperreo
- Lapili (27,312 followers) neoperreo
- Valen Etchegoyen (26,794 followers) argentine trap, neoperreo, latin hip hop
- El Habano (26,254 followers) neoperreo
- ladiferencia2006 (25,922 followers) neoperreo
- MC Buzzz (25,920 followers) neoperreo
- Lizz (25,336 followers) neoperreo
- Niña Dioz (24,354 followers) latin hip hop, mexican hip hop, neoperreo
- Broke Carrey (24,049 followers) argentine trap, neoperreo
- Sinjin Hawke (23,995 followers) neoperreo, gqom, ballroom vogue, uk funky
- LaBlackie (23,545 followers) neoperreo
- Rakky Ripper (23,474 followers) hyperpop, neoperreo
- El Mini (23,152 followers) neoperreo
- Rosa Pistola (22,758 followers) neoperreo, reggaeton mexa, singeli
- pxxr ganggg (22,710 followers) neoperreo
- SIMONA (22,375 followers) neoperreo, latin indie
- Jose Vasquez (22,253 followers) neoperreo
- Mujer Luna Bella (22,187 followers) neoperreo
- dj g2g (21,877 followers) neoperreo
- Mueveloreina (21,455 followers) neoperreo
- Novato El Flow (21,012 followers) reggaeton mexa, neoperreo
- Young Darhi (20,772 followers) chilean trap, neoperreo
- Fuentes Prod (20,696 followers) reggaeton mexa, neoperreo
- El Osito Wito (20,618 followers) rkt, turreo, neoperreo
- Kabasaki (20,528 followers) neoperreo
- LYZZA (20,332 followers) neoperreo
- Sopholov (20,208 followers) reggaeton mexa, neoperreo
- OH!DULCEARi (19,588 followers) neoperreo, hyperpop
- Fuka (19,505 followers) chilean trap, reggaeton chileno, neoperreo
- Virgen Maria (19,175 followers) neoperreo, experimental
- Dam Dam (18,841 followers) reggaeton mexa, neoperreo
- Akatumamy (18,746 followers) neoperreo, reggaeton chileno
- Nick León (17,343 followers) neoperreo, uk funky
- GlorySixVain (17,307 followers) neoperreo
- Sa!koro (17,082 followers) neoperreo, cloud rap
- Gitana (15,561 followers) reggaeton mexa, neoperreo
- Space Surimi (15,242 followers) neoperreo
- Talisto (15,046 followers) neoperreo
- Rico Rosa (15,030 followers) neoperreo
- Kamixlo (14,964 followers) neoperreo, experimental