- Shakira (41,733,669 followers) latin pop
- Luis Miguel (21,659,323 followers) mariachi, bolero, latin pop, ranchera, villancicos
- Ricardo Arjona (14,966,399 followers) latin pop
- Morat (14,379,414 followers) colombian pop, latin pop
- Maná (14,284,938 followers) rock en español, latin rock, mexican rock, latin pop
- Enrique Iglesias (12,284,285 followers) latin pop, latin
- Marc Anthony (11,203,957 followers) salsa, merengue, bachata, latin, latin pop
- Jesse & Joy (10,080,203 followers) latin pop
- Reik (9,961,216 followers) latin pop
- Ha*Ash (9,770,486 followers) latin pop
- Chayanne (9,564,230 followers) latin pop
- TINI (9,472,416 followers) latin pop
- Marco Antonio Solís (9,025,293 followers) grupera, ranchera, mariachi, latin pop
- Alejandro Fernández (8,953,504 followers) mariachi, ranchera, latin pop, bolero
- Alejandro Sanz (8,725,185 followers) latin pop
- Ricky Martin (8,247,235 followers) latin pop
- Ricardo Montaner (6,982,789 followers) latin pop
- Sin Bandera (6,934,216 followers) latin pop
- Carlos Vives (6,926,716 followers) colombian pop, vallenato, latin, latin pop
- Mau y Ricky (6,880,699 followers) latin pop, reggaeton, pop urbano
- Gloria Trevi (6,415,965 followers) latin pop
- Franco De Vita (6,355,089 followers) latin pop
- Yuridia (6,000,077 followers) latin pop
- Juanes (5,753,442 followers) latin pop, colombian pop, rock en español
- Pablo Alborán (5,654,877 followers) latin pop
- Camila (5,376,476 followers) latin pop
- Thalia (5,307,379 followers) latin pop
- Carlos Rivera (5,062,840 followers) latin pop
- David Bisbal (4,889,785 followers) latin pop, villancicos
- La Oreja de Van Gogh (4,784,974 followers) latin pop
- Cristian Castro (4,649,249 followers) latin pop
- Alejandra Guzman (4,325,572 followers) latin pop
- Kany García (3,917,637 followers) latin pop
- Andrés Cepeda (3,910,925 followers) colombian pop, latin pop
- Julieta Venegas (3,617,928 followers) latin pop, latin rock
- Emmanuel (3,617,216 followers) latin pop
- La Quinta Estacion (3,607,426 followers) latin pop
- Fonseca (3,546,492 followers) colombian pop, latin pop
- Río Roma (3,485,298 followers) latin pop
- María José (3,433,368 followers) latin pop
- Miguel Bosé (3,253,601 followers) latin pop
- Sofía Reyes (3,186,886 followers) latin pop
- Paulina Rubio (3,101,395 followers) latin pop
- Alex Ubago (3,027,892 followers) latin pop
- Laura Pausini (2,977,156 followers) latin pop
- Elefante (2,652,551 followers) rock en español, latin rock, mexican rock, latin pop
- Belinda (2,623,663 followers) latin pop
- Miranda! (2,572,715 followers) latin pop
- Mijares (2,570,156 followers) villancicos, latin pop
- Paty Cantú (2,557,470 followers) latin pop
- Diego Torres (2,361,258 followers) latin pop, colombian pop
- Kalimba (2,325,222 followers) latin pop
- Mecano (2,190,523 followers) rock en español, latin pop
- Belanova (2,187,979 followers) latin pop
- Bacilos (2,126,534 followers) colombian pop, latin pop
- RBD (2,123,243 followers) latin pop
- Carlos Baute (2,115,165 followers) latin pop
- Reyli Barba (2,104,167 followers) latin pop
- Playa Limbo (1,989,423 followers) latin pop
- Timbiriche (1,889,958 followers) latin pop, retro pop
- Pedro Capó (1,774,754 followers) latin pop
- OV7 (1,748,019 followers) latin pop, retro pop
- Aleks Syntek (1,741,027 followers) latin pop, rock en español
- Fey (1,426,598 followers) latin pop, retro pop
- Fanny Lu (1,290,124 followers) colombian pop, latin pop
- Santiago Cruz (1,251,659 followers) trova, colombian pop, latin pop
- Gian Marco (1,239,884 followers) colombian pop, trova, latin pop
- Magneto (1,232,294 followers) latin pop, retro pop
- Maite Perroni (1,189,182 followers) latin pop
- Yahir (1,167,183 followers) latin pop
- Sentidos Opuestos (1,143,403 followers) latin pop, retro pop
- Noel Schajris (1,135,207 followers) latin pop
- Moderatto (1,119,696 followers) rock en español, mexican rock, latin pop
- Kabah (1,112,204 followers) latin pop, retro pop
- Mœnia (1,027,849 followers) rock en español, latin pop, latin alternative
- Kudai (1,018,135 followers) latin pop
- Flans (981,427 followers) latin pop, retro pop
- Monica Naranjo (904,590 followers) latin pop
- Ana Torroja (884,062 followers) latin pop
- Tranzas (872,288 followers) latin pop, colombian pop
- Tommy Torres (865,950 followers) latin pop
- Sandoval (865,334 followers) latin pop
- Pasabordo (839,012 followers) colombian pop, popular colombian music, latin pop, ranchera
- Anahí (782,007 followers) latin pop
- Dulce María (760,124 followers) latin pop
- Marta Sánchez (747,476 followers) latin pop
- Cami (733,852 followers) latin pop
- Cabas (695,966 followers) colombian pop, latin pop
- Onda Vaselina (694,895 followers) latin pop, retro pop
- JEANS (619,752 followers) retro pop, latin pop
- Nek (578,768 followers) rock en español, latin pop
- Dragon & Caballero (552,033 followers) colombian pop, latin pop
- Noelia (547,311 followers) latin pop
- LU (544,141 followers) latin pop
- Calo (540,281 followers) latin pop
- Marco di Mauro (509,516 followers) latin pop
- Menudo (502,410 followers) latin pop
- Juan Fernando Velasco (463,887 followers) colombian pop, latin pop
- Obie Bermudez (449,609 followers) latin pop, trova
- Nikki Clan (436,991 followers) latin pop