- 2 Chainz (8,458,559 followers) southern hip hop, rap
- Rick Ross (7,898,390 followers) southern hip hop
- Gucci Mane (6,174,026 followers) southern hip hop, rap, trap
- T.I. (5,272,764 followers) southern hip hop
- Yo Gotti (4,516,918 followers) southern hip hop
- Outkast (3,651,965 followers) southern hip hop, hip hop
- Ludacris (3,547,659 followers) southern hip hop
- Young Dolph (3,478,819 followers) southern hip hop, trap
- Rich Homie Quan (2,940,862 followers) southern hip hop
- Boosie Badazz (2,688,765 followers) southern hip hop, crunk
- Jeezy (2,654,243 followers) southern hip hop, crunk, rap, gangster rap
- Yelawolf (2,398,536 followers) country hip hop, southern hip hop
- BigXthaPlug (2,391,658 followers) southern hip hop
- Plies (2,053,731 followers) southern hip hop
- Three 6 Mafia (1,558,878 followers) southern hip hop, horrorcore, crunk, gangster rap
- DJ Drama (1,454,799 followers) southern hip hop
- Birdman (1,396,577 followers) southern hip hop
- Ying Yang Twins (1,271,758 followers) crunk, southern hip hop
- Lil Jon & The East Side Boyz (1,206,080 followers) crunk, southern hip hop
- Trick Daddy (1,199,457 followers) southern hip hop, crunk
- Webbie (1,191,614 followers) southern hip hop, crunk, new orleans bounce
- JUVENILE (1,178,326 followers) southern hip hop, crunk, new orleans bounce, bounce
- Master P (1,117,636 followers) southern hip hop, gangster rap, old school hip hop, new orleans bounce
- Young Buck (1,101,879 followers) southern hip hop, crunk
- Curren$y (1,073,346 followers) southern hip hop
- Chamillionaire (1,040,123 followers) southern hip hop
- Scarface (1,025,906 followers) southern hip hop, old school hip hop, gangster rap, g-funk
- Project Pat (997,806 followers) southern hip hop, crunk, gangster rap
- Slim Thug (994,575 followers) southern hip hop, crunk
- UGK (974,523 followers) southern hip hop, old school hip hop
- Pimp C (963,719 followers) southern hip hop, crunk
- Big K.R.I.T. (954,859 followers) southern hip hop
- Paul Wall (943,431 followers) southern hip hop, crunk
- Bun B (928,705 followers) southern hip hop
- David Banner (923,305 followers) southern hip hop, crunk
- Gorilla Zoe (917,774 followers) southern hip hop, crunk
- Yung Joc (900,154 followers) crunk, southern hip hop
- Young Dro (889,217 followers) southern hip hop, crunk
- Geto Boys (870,615 followers) old school hip hop, southern hip hop, gangster rap, g-funk, hardcore hip hop, horrorcore
- Lil Scrappy (845,832 followers) crunk, southern hip hop
- Mystikal (811,745 followers) southern hip hop, crunk, old school hip hop, gangster rap
- Mike Jones (721,656 followers) southern hip hop, crunk
- Z-Ro (713,419 followers) southern hip hop
- Big Tymers (703,136 followers) southern hip hop, crunk, new orleans bounce
- Adam Calhoun (693,017 followers) country hip hop, southern hip hop
- Boyz N Da Hood (687,562 followers) southern hip hop, crunk
- Lil Wyte (676,647 followers) country hip hop, southern hip hop, crunk
- Petey Pablo (675,375 followers) crunk, southern hip hop
- B.G. (669,454 followers) southern hip hop, new orleans bounce
- Lil' Flip (652,810 followers) southern hip hop, crunk
- Youngbloodz (648,735 followers) crunk, southern hip hop
- Struggle Jennings (638,723 followers) country hip hop, southern hip hop
- Pastor Troy (597,287 followers) southern hip hop, crunk
- Rocko (586,220 followers) southern hip hop
- Jermaine Dupri (547,163 followers) southern hip hop
- C-Murder (526,957 followers) southern hip hop, crunk, new orleans bounce
- Dem Franchize Boyz (523,215 followers) crunk, southern hip hop
- Crime Mob (502,958 followers) crunk, southern hip hop
- DJ Screw (502,250 followers) southern hip hop, gangster rap, crunk
- Killer Mike (501,908 followers) southern hip hop, alternative hip hop
- 8Ball (491,030 followers) southern hip hop, crunk
- Do Or Die (473,218 followers) southern hip hop
- Haystak (472,868 followers) country hip hop, southern hip hop
- Big Boi (463,465 followers) southern hip hop
- Bubba Sparxxx (445,594 followers) country hip hop, southern hip hop
- Shawty Lo (437,280 followers) southern hip hop, crunk
- Trillville (396,913 followers) crunk, southern hip hop
- 8Ball & MJG (393,131 followers) southern hip hop, crunk, old school hip hop
- Lil' Keke (392,155 followers) southern hip hop, crunk
- Rich Boy (389,968 followers) southern hip hop, crunk
- D4L (375,027 followers) crunk, southern hip hop
- OJ Da Juiceman (371,616 followers) southern hip hop, trap
- Devin The Dude (371,116 followers) southern hip hop, g-funk
- MJG (369,996 followers) southern hip hop
- Silkk The Shocker (368,576 followers) southern hip hop, new orleans bounce
- Starlito (363,784 followers) southern hip hop
- Soulja Slim (362,836 followers) southern hip hop, new orleans bounce, bounce
- Hurricane Chris (360,323 followers) southern hip hop, crunk
- Bone Crusher (343,276 followers) crunk, southern hip hop
- Moonshine Bandits (326,371 followers) country hip hop, country rock, southern hip hop
- Big Moe (307,598 followers) southern hip hop
- U.S.D.A. (306,014 followers) southern hip hop, crunk
- Goodie Mob (303,512 followers) southern hip hop, old school hip hop
- Field Mob (302,278 followers) southern hip hop
- Fat Pat (297,880 followers) southern hip hop
- Mannie Fresh (267,314 followers) southern hip hop, new orleans bounce
- Unk (262,622 followers) crunk, southern hip hop
- Trae Tha Truth (257,707 followers) southern hip hop
- Nappy Roots (256,622 followers) southern hip hop
- 504 Boyz (235,660 followers) new orleans bounce, southern hip hop
- DeeBaby (234,009 followers) southern hip hop
- Gangsta Boo (208,839 followers) southern hip hop, horrorcore, crunk
- Big Pokey (207,739 followers) southern hip hop, crunk
- Tear Da Club Up Thugs (196,888 followers) southern hip hop, crunk
- TRU (187,667 followers) southern hip hop
- Hot Boys (187,546 followers) southern hip hop, new orleans bounce
- Foxx (178,227 followers) southern hip hop, crunk, new orleans bounce
- Young Bleed (174,462 followers) southern hip hop, new orleans bounce
- CunninLynguists (172,128 followers) underground hip hop, southern hip hop, hip hop
- Mia X (166,929 followers) southern hip hop, new orleans bounce