- Andrea Bocelli (3,317,936 followers) classical crossover, opera
- Lindsey Stirling (2,475,859 followers) classical crossover, christmas
- The Piano Guys (1,350,213 followers) classical crossover
- Luciano Pavarotti (1,151,066 followers) opera, classical, canzone napoletana, classical crossover
- 2CELLOS (1,138,168 followers) classical crossover
- Josh Groban (1,058,714 followers) classical crossover, christmas
- Il Divo (947,968 followers) classical crossover, opera
- Il Volo (806,059 followers) classical crossover, opera
- Celtic Woman (574,573 followers) celtic, classical crossover
- David Garrett (530,543 followers) classical crossover, classical
- Sarah Brightman (511,611 followers) classical crossover, opera, musicals
- Dimash Qudaibergen (465,279 followers) classical crossover
- HAUSER (381,509 followers) classical, classical crossover
- Secret Garden (294,770 followers) new age, celtic, classical crossover
- Natasha St-Pier (272,500 followers) variété française, chanson, french pop, chanson québécoise, classical crossover
- Susan Boyle (264,445 followers) classical crossover, christmas
- Gregorian (239,210 followers) gregorian chant, new age, classical crossover
- Plácido Domingo (232,864 followers) opera, classical, classical crossover
- Simply Three (205,509 followers) classical crossover
- Forestella (202,585 followers) classical crossover
- José Carreras (168,225 followers) opera, classical crossover, classical
- Matteo Bocelli (161,701 followers) christmas, classical crossover
- Vanessa-Mae (151,382 followers) classical crossover, electronic classical, new age
- Katherine Jenkins (150,610 followers) classical crossover, opera, classical
- Rondò Veneziano (126,910 followers) classical crossover, electronic classical
- Bond (120,490 followers) classical crossover, electronic classical
- Black Violin (112,986 followers) classical crossover
- Jackie Evancho (108,233 followers) classical crossover, opera
- Cecilia Bartoli (103,931 followers) opera, baroque, classical crossover, classical
- Libera (101,376 followers) choral, classical crossover
- Hayley Westenra (96,073 followers) classical crossover, celtic
- Christine McVie (81,466 followers) classical crossover, yacht rock
- Josh Vietti (78,676 followers) classical crossover
- Lucy Thomas (69,507 followers) classical crossover
- Alessandro Safina (67,643 followers) classical crossover
- Kevin Olusola (67,611 followers) classical crossover
- E.S. Posthumus (66,818 followers) classical crossover
- Sissel (66,430 followers) christmas, classical crossover
- Abel Selaocoe (65,539 followers) classical crossover, contemporary classical
- Emma Shapplin (62,161 followers) classical crossover, new age, opera
- Escala (61,809 followers) classical crossover
- Collabro (59,424 followers) classical crossover
- Michael Ball (58,383 followers) classical crossover, musicals
- Paul Potts (57,211 followers) classical crossover, opera
- William Joseph (54,755 followers) classical crossover
- Filippa Giordano (54,545 followers) classical crossover, opera
- Anúna (53,517 followers) celtic, classical crossover, choral, medieval, gregorian chant
- Alfie Boe (53,149 followers) classical crossover, musicals
- The Canadian Tenors (53,149 followers) classical crossover
- Eklipse (51,144 followers) classical crossover
- The Tenors (47,181 followers) classical crossover, christmas
- Russell Watson (45,267 followers) classical crossover
- Alberto Urso (44,663 followers) classical crossover
- Dallas String Quartet (43,908 followers) classical crossover
- Charlotte Church (42,977 followers) classical crossover
- Break of Reality (39,839 followers) classical crossover
- Caitlin De Ville (37,821 followers) classical crossover, polka
- Amira Willighagen (37,530 followers) opera, classical crossover
- The Ten Tenors (37,437 followers) classical crossover
- Chloe Agnew (36,980 followers) celtic, classical crossover, new age
- Jonathan Antoine (36,330 followers) classical crossover, opera
- Mario Frangoulis (35,735 followers) classical crossover, entehno, laïko
- Jacques Loussier Trio (35,569 followers) jazz, classical crossover
- Luka Sulic (33,631 followers) classical crossover
- Jennifer Thomas (32,617 followers) classical crossover
- Jacques Loussier (32,061 followers) jazz, classical crossover
- John Deacon (31,752 followers) classical crossover
- Bryn Terfel (28,359 followers) opera, classical crossover, classical, choral
- Romanz (27,490 followers) afrikaans pop, gospel, classical crossover
- Natalie Dessay (27,402 followers) opera, classical crossover
- Czech Philharmonic (26,726 followers) classical, orchestral, classical crossover, concerto
- Saint-Preux (25,389 followers) classical crossover
- Miriam Stockley (25,381 followers) new age, celtic, classical crossover
- All Angels (25,248 followers) classical crossover
- Patrizio Buanne (25,060 followers) schlager, classical crossover
- Helmut Lotti (23,973 followers) classical crossover
- MAKSIM (23,835 followers) classical crossover
- Igor Krutoy (22,197 followers) classical crossover
- Ekseption (22,088 followers) nederpop, progressive rock, classical crossover
- Giorgia Fumanti (22,018 followers) classical crossover, opera
- Nathan Pacheco (21,961 followers) classical crossover, hymns
- Edvin Marton (21,465 followers) classical crossover, electronic classical
- Lexi Walker (20,848 followers) classical crossover
- Amici forever (20,714 followers) classical crossover, opera
- Méav (20,560 followers) celtic, sea shanties, new age, classical crossover
- Lisa Kelly (20,086 followers) celtic, classical crossover
- John Riesen (19,996 followers) classical crossover, neoclassical
- Laura Bretan (19,534 followers) classical crossover
- →Pia-no-jaC← (19,421 followers) jazz fusion, classical crossover
- Sumi Jo (19,411 followers) opera, classical crossover, classical
- Aled Jones (18,884 followers) classical crossover, christmas
- Eugen Cicero (18,416 followers) jazz, classical crossover
- Jonathan & Charlotte (18,165 followers) classical crossover, opera
- Lucia Micarelli (17,276 followers) classical crossover
- 92 Keys (17,179 followers) classical crossover
- Vittorio Grigolo (17,116 followers) classical crossover, opera
- Chris Mann (16,925 followers) classical crossover
- Patricia Janečková (16,888 followers) classical crossover, opera
- Aida Garifullina (16,298 followers) opera, classical crossover
- The Irish Tenors (16,009 followers) celtic, classical crossover