- Frei Gilson (1,630,264 followers) gospel, catholic music, worship
- Colo de Deus (1,176,456 followers) catholic music, worship, gospel
- Matt Maher (468,540 followers) christian, worship, catholic music, ccm, pop worship
- Eliana Ribeiro (329,539 followers) catholic music, gospel
- Comunidade Católica Shalom (300,307 followers) catholic music
- Ministério Adoração e Vida (291,968 followers) catholic music, gospel, brazilian gospel, worship
- Hakuna Group Music (286,090 followers) catholic music, villancicos
- Fraternidade São João Paulo II (252,232 followers) catholic music, gospel, worship
- Irmã Kelly Patrícia (235,996 followers) catholic music
- Athenas (228,130 followers) catholic music, worship
- Son By Four (225,655 followers) salsa, catholic music
- Tony Allysson (216,764 followers) gospel, catholic music
- Vida Reluz (201,422 followers) gospel, catholic music
- Missionário Shalom (196,264 followers) catholic music
- Hermana Glenda (196,189 followers) catholic music, christian
- Juninho Cassimiro (173,850 followers) catholic music
- Walmir Alencar (163,359 followers) catholic music
- Audrey Assad (160,499 followers) hymns, worship, catholic music, christian, ccm
- Martín Valverde (124,092 followers) catholic music, christian
- Toca de Assis (120,793 followers) catholic music
- Jésed (116,960 followers) catholic music
- Flavio Vitor Jr. (111,910 followers) catholic music
- Ministério Amor e Adoração (111,045 followers) catholic music
- Ziza Fernandes (106,173 followers) catholic music
- Davidson Silva (104,120 followers) catholic music
- Dunga (95,002 followers) catholic music
- Jon Carlo (86,011 followers) catholic music
- Taizé (79,121 followers) gregorian chant, catholic music, hymns
- Instrumental Christian Songs, Christian Piano Music (70,143 followers) catholic music, christian jazz, hymns
- Harpa Dei (69,350 followers) gregorian chant, catholic music, hymns
- Irmã Ana Paula, CMES (67,246 followers) catholic music
- Bukas Palad Music Ministry (66,744 followers) catholic music, worship
- Alfareros (64,682 followers) catholic music
- Cantores De Deus (64,605 followers) catholic music
- Diego Fernandes (62,838 followers) catholic music
- Kairy Marquez (59,710 followers) catholic music
- Pablo Martinez (56,146 followers) catholic music
- Macecilia A St Paul (56,053 followers) gospel, catholic music, traditional gospel
- Marco Frisina (53,454 followers) gregorian chant, catholic music, hymns
- Fraternidade O Caminho (52,803 followers) catholic music
- Celines (48,810 followers) catholic music
- Ge'La (48,068 followers) catholic music, christian
- Giovanni Pierluigi da Palestrina (47,927 followers) renaissance, choral, early music, gregorian chant, catholic music, classical, medieval
- Gabriela de Sá (46,904 followers) catholic music
- Gerados pela Imaculada (46,811 followers) catholic music
- Grupo Nueva Vida (46,032 followers) catholic music
- Cristóbal Fones, Sj (45,661 followers) catholic music
- Musica Catolica (45,547 followers) catholic music
- Alabanzas A Cristo (42,952 followers) catholic music
- John Michael Talbot (42,740 followers) catholic music, hymns, christian folk, ccm, christian
- Verónica Sanfilippo (42,194 followers) catholic music
- Flavinho (41,775 followers) catholic music
- Gregorian Chant (38,350 followers) gregorian chant, japanese classical, catholic music, hymns
- Siervas (36,960 followers) catholic music
- Benedictines of Mary, Queen of Apostles (36,829 followers) gregorian chant, catholic music, hymns, choral
- Canto Católico (36,508 followers) gregorian chant, catholic music, villancicos
- Fruto del Madero (36,443 followers) catholic music
- Monks Of The Abbey Of Notre Dame (36,361 followers) gregorian chant, catholic music, medieval, hymns
- Fátima Souza (36,291 followers) catholic music
- Gil Monteiro (35,707 followers) catholic music
- The Tallis Scholars (33,919 followers) renaissance, choral, early music, gregorian chant, medieval, catholic music, baroque
- Cristo Alegria (33,239 followers) catholic music
- Coro Pascua Joven San Isidro (31,951 followers) catholic music
- Sarah Kroger (31,519 followers) catholic music, worship
- Stellenbosch University Choir (31,231 followers) choral, catholic music, gregorian chant
- Alabanza Musical (30,816 followers) villancicos, catholic music
- Dei Verbum (30,785 followers) catholic music
- Mariolita Gonzales (30,643 followers) catholic music, pentecostal music, christian
- Catholic Lofi (30,130 followers) christian lo-fi, catholic music, lo-fi, gregorian chant
- Himig Heswita (28,258 followers) catholic music, worship
- Estación Cero (28,042 followers) catholic music, christian rock
- Patrick Lenk (27,588 followers) gregorian chant, catholic music, hymns
- Joan Sanchez (27,508 followers) catholic music
- Brother Isaiah (27,212 followers) catholic music, christian folk
- Cantos catolicos (27,164 followers) catholic music
- The O'Neill Brothers Group (26,692 followers) hymns, catholic music
- Yuli y Josh (26,123 followers) catholic music
- The Hillbilly Thomists (25,966 followers) christian bluegrass, catholic music, christian folk, bluegrass, country christian
- Coral Católica (25,492 followers) catholic music
- Emanuel Stênio (25,365 followers) catholic music
- Gregorian Chants (25,275 followers) gregorian chant, catholic music, hymns, medieval
- Jon Sarta (24,814 followers) catholic music, ballet
- Kiko Argüello (23,839 followers) catholic music
- Jesse Demara (23,539 followers) catholic music
- tuyo (23,171 followers) catholic music
- Arautos do Evangelho (23,111 followers) gregorian chant, catholic music
- niemaGOtu (23,100 followers) catholic music
- Mai Thiên Vân (21,945 followers) vietnamese bolero, bolero, catholic music
- Divna Ljubojevic (21,463 followers) gregorian chant, hymns, catholic music
- Wonderworker (20,846 followers) gregorian chant, catholic music, hymns
- Cantantes De Dios (20,781 followers) catholic music, christian
- The Cathedral Singers (20,628 followers) gregorian chant, catholic music, hymns, choral
- Luis Enrique Ascoy (20,482 followers) catholic music
- GBA Stage (20,228 followers) catholic music
- Olívia Ferreira (20,180 followers) catholic music
- The Sun (20,171 followers) catholic music
- Cantos do Hinário Litúrgico da CNBB (20,155 followers) catholic music, gregorian chant
- Sir Jude Nnam (20,041 followers) hymns, catholic music
- Seraphim Bit-Kharibi (19,978 followers) gregorian chant, hymns, catholic music
- Felipe Gomez (19,883 followers) catholic music